I'm not sure about Monkey specifically, but I know Line 6 products in general and the X3 in particular are not yet supported under Windows 7. Different users have differnet experiences but most have some seem to have some problem or other. But I believe you can run applications under Windows 7 in compatibility mode, and I believe people have had some success with Monkey/X3 doing this. I don't think you can harm anything - just give it a try. I think worst case is it won't work.