Yeah Jim makes a good point about routing. At the moment, your best bet for a good re-amping solution is the HD Pro, as it has a dry guitar output. The HD500 doesn't have this, nor does it have the ability to split dry and wet signal across the USB output. There is a workaround involving using path A for dry and path B for wet, then panning them hard left and right but tbh, I'm not too keen on that idea. It means you have to record everything mono.

Will the HD500 get dry/wet capabilities through a software update? Who knows. It must be possible!

Here are a couple of good resources, both form Line 6 forum users: MerlinFL and meambobbo:

http://line6.com/support/thread/77774

http://line6.com/support/thread/71651?tstart=0  and http://foobazaar.com/podhd/toneGuide/index.html

Mlynch74d3 wrote:

 

.... There is a certain appeal in downloading real good patches that nail the tone I'm looking for with no work involved,...

Yes, that's a nice dream - but the reality is that there are so many other factors that affect the final tone. Each patch loaded up to Cutomtone was created in a specific environment: a certain guitar with specific pickups and tone/volume settings, a certain amp or pair of speakers, or headphones, etc...... All of these things contribute to the final sound. And what may have sounded great in the environment where it was created will not sound anything like that in the environment of the preson who downloads the tone and uses it with different equipment. There is almost always a need to tweak the tone substantially in your own environment. And the best way to understand how they should be tweaked is to become familiar with creating your own tones. That really is the best way to start. Customtone will become more valuable to you after you understand how your own equipment works best with the Pod HD.

EDIT: Here's another useful resource:

http://line6.com/support/docs/DOC-2525