Currently Being ModeratedOct 17, 2011 10:06 AM (in response to SlapGas)RE: POD X3 Live into a Marshall JCM2000 TSL 100
If you are familiar with the four cable method, I would suggest you use that to enable you to route distortion/amp model effects to the front end of the clean channel on your amp. You then will be able to use the effects loop for modulation/delay effects. For info on using the Four cable method, visit the link below:
If you do use a amp model, I would suggest to not use the cab model, because you are running it through a cabinet already. However, if you don't like the sound of not using cab sims, then I would use them. It is all up to you as to what you think sounds good for your music and playing style.