I recently tried a registry clean program using windows XP right after I updated to the latest driver 4.2.5.1

As I was using the Line 6 edit the pod HD500 restarted and I lost all sounds. I tried repowering the POD but it kept getting stuck looping the startup screen with no sound. The Quick fix was to power up as I press the left arrow on 4 way button. Few minutes after recalibrating the POD continuous controller, and after connecting using USB and using Line 6 edit the POD again started looping trying to restart without sound. The second time the Left arrow thing worked perfectly so I decided not to connect USB. For a couple of hours without using the USB edit program the POD was fine using its own hardware front Panel. I decided to try again with USB sure enough same problem and same fix.

I became suspicious that the Registry cleaner was the culprit so I restored my system from a ghost image before the registry cleaner was installed and all is good.  The concern is that the restored system has the older USB driver right before 4.2.51. I decided not to update yet even though I think the registry cleaner is the culprit and it's probably safe for me to update to 4.2.51 but I want to bring that up to everyone’s attention that the left arrow can be a fix for the startup loop. My question is somewhat answered but I'll ask it any way, Is the USB communication using Line 6 edit capable of doing that kind of POD malfunction? And what can we do to prevent this sort of things from happening? I will soon update to the latest driver to confirm that the Registry cleaner messed up my windows XP Sp 3 system to cause the driver malfunction.

Just want to add that I didn't intend to alarm anyone because this behavior is sometimes common when using a PC to communicate with MIDI instruments. I've had similar experience with Roland Synth where the synth would completely freeze sometimes when used with PC sequencer. It's just an unfortunate consequence of using an operating system that is intended to do million other tasks. I hope some music only operating system will be implemented by some entity, that will make it easier to get to the bottom of this problem without having to worry about so many features of massive operating systems like Windows or Mac...

Edit: Just updated to 4.2.5.1 driver and been playing for 4-5 hours using the Line 6 Edit and no problems, which in my situations means that the Registry editor program was the main cause of the problem.