Is anyone but me thinking the behavior when using this feature is kind of strange.  There's a strange default thing going on.  I tried setting up the tone control to control the drive on the treadplate(which amp probably doesnt matter). If I change the tone control to change the amount of drive and then change the pick up selector it will change the drive tone to a default setting, which I believe is with the tone at 100%.  The other thing that was happening is that if I set it up so that the drive at the lowest of the two settings is with the tone control at zero, so as I turn up the tone control I get more drive but save the preset with the tone on zero (cleanest setting).  If I go to a different patch and then back the tone is really dark, like the actual tone of the guitar is working even though I locked it out.  I have to move the tone control to get the brightness back again.   This is a good example to explain the other issue as well. So the default is tone on zero but if I change the pickup selector, it acts like the tone is on 100% it doesn't matter where the tone knob physically is, and I have the highest drive setting.  It's just strange and difficult to use.

In the interim, I have done the counter-intuitive thing and reversed it so the lowest amount of drive is with the tone on full and then backing ofnthe tone control increases the drive.  At least then when I hit the preset footswitch I have the bright tone, and the default when changing pickups is the crunch, but it still has a set of challenges.

I'm hoping no one else has this issue and that I just need to reflash something.  Or that it's a known issue and Line 6 is on it.   I really hope this wasn't the intention.

If you are going to use the tone knob to control a parameter on the HD500 and you lock it out, you should be able to save it at your preferred tone setting.   And the pick up selector shouldn't change what you have the tone knob set at.