I browse the Variax JTV and HD forums pretty often but rarely say much. But I don't see anybody using the HD 500 quite like I do so I thought I'd throw in my 2 cents. I have a JTV 69 (with a transplanted 1986 Ibanez Wizard neck on it) mated to the HD500 and I couldn't be happier with it. I preset everything for a service using the edit program. I plug directly into the church mixer and we have Aviom units for personal monitoring.
This is only practical is you interface to a PC, and use POD HD500 Edit at home to set the HD up for a service ahead of time. Since our services are preplanned, and have 5 to 9 songs (depending on if it is a Communion service), I use Set List Bank One for the song selections of the week. The 1st song goes in 01A. I can have up to four sounds for song #1 (e.g. 01A-interesting intro sound, 01B-acoustic model, 01C-distorted power chords, 01D-pretty and clean tremolo for an easy ending). Song #2 goes in 02A, 02B, 02C. and maybe 02D. Song #3 in 03A, B, C, D etc. I can pre-program up to 16 songs that way. If the band is starting the 7th song, I just have to make sure I have the HD on 07A to get started right.
I named Set List Bank Two, "Scratch Pad", and use it to throw presets into for experimentation, or to copy the Bank One service selections into as a back-up.
The remaining six banks are named, "Acoustic", "Clean", "GP Crunchy" (GP=General Purpose), "Overdrv to HiGain", "Riffs/FX/Bass", and "Processed/Other". I can put up to 64 (16X4) presets in each bank. I spent several enjoyable evenings on-line down-loading and auditioning presets, and keeping the ones I liked and thought were useful or just fun. I equalized them for initial volume, and made sure the foot pedal was configured as a volume pedal (I'm addicted to having one). Then I put the presets in the appropriate bank (Acoustic, Clean, Crunchy, etc) to create a local library. Now, when I am looking for a certain sound for a certain song, I can go to the appropriate bank and usually find something close. I copy that one to Bank One for the service, fine-tune it, and give it the name of the song. e.g. Slot 01A might become, "Our God Saves 1", 01B would be "Our God Saves 2", etc. Then I also save these re-named presets to the PC so the next time they are used for a service, I just pull them back, load them into the appropriate spots in Bank One, and I am ready to go.
This has worked great for me. I have hundreds of organized, pre-screened presets to pick from when arranging songs. I have all of our old songs on the PC, ready to pull up by name, and load into Set List One for a service. With the JTV/HD500 rig, I can go from a 12-string acoustic to a screaming Les Paul with the push of a footswitch. Or drop the high-E string a half-step for songs like "My Reward" with another push of a button. What a fun blessing! I hope this helps someone.