Good morning, I've recently upgraded my home setup to a 27" Imac Quad 2.9Ghz with 8Gb RAM and since experiencing issues with my UX2 sound intermittently cutting out every couple of seconds, I've installed and reinstalled all drivers and firmware various times with no success and exceptional frustration. Output issues are consistent with all sound applications (i.e. PODFarm, iTunes, GuitarPro etc.). If I bypass the UX2 in the likes of iTunes and GuitarPro the issue's gone immediately.
I've done all the usual troubleshooting with no success, I've googled and found this to be a well known issue with Line6 UX2 and other products on the OSX 10.8.