There's no guarantee that it'll fix it either. I'm not 100% sure what causes it but sometimes it has to do with the piezo.
The thing is, it's usually more or less to do with if you have a plunking noise when palm muting, and not just the E string in general sounding off compared to the other strings.
Now, most guitars naturally do have a bit of a overtone on the 6th string that the other strings don't have, but the problem is that it's over-exaggerated on these problem Variax guitars.
If I switch between mags and spank on my 69s, all the strings except the 6th string sound very identical, and the 6th string has thing clanky overtone.
Again, it's natural, but over-exaggerated, and it shows when playing.
It's at it's worse when you tremolo pick the E string. Laying the pick flat instead of slanted helps reduce the sound.
Either way, it's kind of a "live with it" thing at this point for me.
My very first Variax sounded perfect, but I thought there was an issue with the processor (sadly it was just a firmware glitch)
My first replacement, I noticed the 6th string sounding awkward, so I asked for another replacement.
My final guitar that I have now still has the problem.
Some people argue that it's normal because it's hard to point out unless you are actually playing the guitar, but I really do think it's an issue, because like I said, my very first guitar didn't have this problem.