quick response, then let's stay on topic.
i think there's a couple ways to go. first of all, i often use "dual cab" patches, so I can get the nice bass and punch of the XXL with a brighter cab. For live use, this is pointless. You can get rid of channel B completely - the amp settings (other than EQ) should be identical. This will give you room for more EQ's, or wah pedals, or a harmony, or to move from a regular to a spring reverb.
As for EQ, I tend to find for my rig, I have to turn down the Master DEP a bit or use the pre-amp version of the amp model to get the clean brightness I want. As for cabs, I tend to like "no cab", but I also find the Treadplate works nice with my rig - it gives it the presence boost it needs to really bite. You could get the same thing via EQ effects, but I like to use the cab as a starting point. The rest really depends on your rig.
At some point I do plan to translate them all to "live" patches to make a live setlist, but who knows when?