When running Native as a plug-in within a large DAW recording project, there's often a trade-off between monitoring through the plug-in/DAW vs latency (delay between playing the guitar and hearing the guitar through the software/hardware). In Logic, I often have to set my buffer up pretty high in order to prevent audio glitches if I want to monitor through Helix Native when recording a new guitar track. For me, its important to hear the sound of a guitar modeler and its effects in order to get the mojo of the track while recording. Yeah, I can use a guitar modeler in my Apollo Twin DSP, and monitor that in real-time, but its not the same. It's workable but not ideal. That's a big trade-off.
I recently bought a copy of S-Gear (another popular amp/cabinet and effects modeler). Its not as extensive as Helix Native, but for the included amps I actually prefer its tone and response. But the HUGE benefit is that the software includes a stand-alone application identical to the DAW plug-in. Now I can set up routing through my audio interface so that I can monitor the sound of the S-Gear amps and effects through the standalone app with very low latency (8.5 ms), while recording the guitar along with my existing Logic tracks. I can leave my Logic buffer set high for large track and virtual instrument counts, and still have low latency when monitoring my amped guitar. Its delicious. And, like Native, I can choose to record the raw track, or the S-Gear processed track.
Sadly, Helix Native does not include a standalone app. If there was one (and it would need to be a low-latency application), users would be able to 1) monitor their guitar modeling with near zero latency when recording tracks and 2) play through the app without having to fire up their DAW, load the plug-in, etc.
P.S. There are standalone apps that will host plug-ins out there. That might work for this usage, but I haven't tested it. Worth a try!