2 Guitarists In The Band: Me With Hd500 To Pa, The Other With Real Amp in POD HD Posted July 17, 2013 If you roll the flab off the 15' bass it tightens up but better it gives a tight defined bottom end. When all players have an Amp combo or cabinet there is an isolation in the sound stage. But if two guitars both have say 2x12 cabs, they risk washing each other out. The first way to differentiate their tone is to lift one of the amps off the floor. You can check this with your own Amp, on the floor the bass is hyped. Lift it up onto a chair more mids, higher onto a table, more top end and might get a little thin. Bass is ambi directional and is best on the floor fairly centered with the drums. Rhythm guitar could be a nice warm 4x10 or 2x!2 horizontal flat on the floor. Lead could be single 12' on a crate or 2x12 upright stack If you think in those terms into a PA you got some cutting to do as the speakers up on stands are going to accentuate the bright and if you crank the bottom end to fill it out so it sounds balanced , no one else will be heard.