I've opened a ticket about this but want to hear from any other Windows 11 based DAW users who may have ran into the same issue.
The latest Windows 11 Pro 64-bit OS update a couple of days ago caused a hole in security due to Line 6 driver incompatibility on my hardware DAW, a DELL XPS 8940, 11th Gen Intel i9-11900K processor (8-Core, 16M Cache, 3.5GHz to 5.3GHz), with 64GB RAM, running Windows 11 Pro 64-bit. Its a stripped down system optimized for audio production. The OS Memory Integrity switch cannot be toggled to on due to conflicts with these Line 6 drivers. (see screen caps attached)
I6Helix_AvsFilter.sys
I6HXStomp_AvsFilter.sys (for some reason has 2 instances)
I6PodHd2_AvsFilter.sys
I have related problem on a Surface Book 2 laptop that I previously used as a DAW and uninstalled all Line 6 software on but it did not successful remove all Line 6 drivers, specifically the I6HXStomp_AvsFilter.sys file which I cannot find to manually remove. I have parsed through Microsoft documents for deleting unruly drivers but the system still thinks the driver is installed.