I've been using the M13 for 5...6 years now. The thing I like most about the M13 is that I can run my effects in front of the amp like a traditional pedal board. I like the fact that my M13 is a TRUE BYPASS unit.
I also have the HD500. My only complaint about the HD500 was that it wasn't a TRUE BYPASS. I'm not interested in the amp modeling like some guitarists are. I just want to use the effects only without the HD500 coloring my Mesa Boogie Dual Rectifier's tone. So I never used it