I've had this driver incompatibility issue crop up also when installing HX Edit for the first time on a one year old Windows 11 laptop (Dell 9710, Windows 11 Pro Version 22H2, HX Edit version 3.50). Previously was running HX Edit on a different computer (which didn't support Memory Integrity).   As folks here have noted, turning off Memory Integrity seems to be the accepted solution, even according to Microsoft (https://support.microsoft.com/en-us/windows/why-do-incompatible-drivers-pr