So if you were thinking of replacing your Mackie with the TT as your main recording interface I wouldn't do it. As a preamp in front of it then sure but I don't know that the amp models and effects are really worth the extra complexity. You still need an iOS device to adjust the tones so now its three devices, the TT, the Mackie, and an iPad. I wish Line 6 would develop a desktop module like Amplitube.