Thank you for the reply rd2rk.
The setting you proposed did not work (that was the setting I had), but changing the Presets, INPUT BLOCK setting, to 1M fix the issue.
Interesting is that I don’t use wireless, but I use the Neutric SilentPLUG (Mogami Gold Cable). Maybe that’s the reason? Or maybe my pickups are just acting strange (old Aria Pro II guitar with humbuckers)
In any case, the issue is resolved by this setting.
Thank you for your help on this.