I installed windows 10 yesterday and I had no sound at all with my UX2 (which had previously been excellent). I discovered it was the bit depth of the driver causing the issue, if you change the bit depth to 16 Bit 48000 you should be fine, although this does not solve many problems as much of the software I have requires 24 bit depth. The ASIO drivers also work (ish), I trust the Line 6 team will be working hard to get the new fully compatible drivers out. Please remember though that windows 10 has a whole new system for audio so a little additional time for the team to develop drivers that work well should be expected, you would be more unhappy if they released drivers that only partially worked. Although I understand their delays in releasing compatible drivers, I have to say I am disappointed, I have spent a great deal of money on line6 equipment and to date it has not let me down but the drivers leave a lot to be desired. If they want people to spend money on hardware and software then surely they should prioritise the development of good quality drivers, its not like Windows 10 was only announced last week and launched with no notice.