It appears that there is an issue with the LA Comp.   You likely won’t notice it if you use it before the amp block as it doesn’t do much to the over all volume in that position.  However if you put it after the amp block it will affect the volume of the patch and as a result depending on how it’s feeling when you load the preset you may get full volume and you might get less than full volume (as I said it’s random).   I started using the compressor at the end of the chain af