I used to suffer from these two issues, tuning changes with changes in intensity of playing, and of course the dreaded intonation. But with a good set up and the right calibre of strings (switched from lights to light top heavy bottom) I've had no further issues. My only complaint with regards to the HD series is the tuning is not able to calibrate to 442 for those rare occasions when I've played with orchestra. That's when I go to my old Boss, that, after 15 years (no joke) it hasn't broken or failed once! Line 6 needs to find a way to upgrade the software for this function.