Hello everybody!
I can confirm the issue because I'm also unable to use the POD GO as an audio interface for Reaper (but the problem is a general problem and not limited to any specific DAW).
My system is a POD GO (v1.12) and Windows 10. I'm also forced to use an additional audio interface for recording.
The issue may be described with the following statements:
The USB input level for any input (1-4 from PodGO -> PC) is too low for proper usage
The Windows10 driver lacks a function to increase the input level (decreasing is possible)
There is no "Master USB-Output Level" on the POD GO that allows a general adjustment for the USB output level
At least there is a workaround to get to usable output levels: increase the "Main-Out" output level at the end of each preset. Adding 12-18dB does the job in my case.
However I'm not really happy with that, because every single preset needs to be adjusted which also affects non-USB output levels (leading to even more unwanted side-effects). Additionally it would also mean, that all Factory-Presets are levelled too low and need corrections (I'd suppose that the reference-factory presets should have a usable level at the end of the preset chain).
Hope this hint helps until the missing feature is implemented ... there's no adjustment in the Global Settings in v1.12 for output (as pointed out by woffles) - only for input.