New bass cabs are also crashing Helix Native 3.52 in Studio One 6.0.2 under Windows 11 for me. I usually run with hardware compatibility mode turned off, but I switched it to the default, reimported the 3.5 setlists, and the bass presets still cause a crash. I haven't tried it with the 3.50 release yet, but I did try uninstalling and reinstalling.
UPDATE: Falling back to 3.50 or 3.51 fixed the crashes for me. The crashing problem seems to be new in Helix Native 3.52.