The DI on the Spider IV is really a STEREO headphone out..  We were running it direct into the mixer for gigs (1/4") and it sounded pretty good but something just wasn't right....  Unless your taking the signal out of the DI with a TRS "Y" splitter and running 2 separate signals to either 2 separate channels (or a stereo input) on the mixer, you're only getting half of the sound (it is stereo)... 
  
  It's VERY, VERY BAD to combine a stereo signal into 1 with a "Y" cable http://www.rane.com/note109.html  (good read) so we tried one of these: 
  
http://www.bhphotovideo.com/c/product/160658-REG/Hosa_Technology_TRS_202_Stereo_1_4_Male_to.html 
  
  
Into one of these: 
  
http://www.bhphotovideo.com/bnh/controller/home?O=&sku=333335&Q=&is=REG&A=details 
  
and out to the mixer/snake via XLR....  WHAM!!!  The sound was there,, all of it...  Full, big and cutting. 
  
Try it,,, You'll like it!!! 
  
PS... I sprung for one of these to add versatility (can run IPod to PA and have a COMBINED mono signal.. 
  
http://www.rolls.com/product.php?pid=DB14