I've been having USB flakyness with Windows 10 as well. My Gigabyte motherboard has USB 3.0 support, but compatibility with different devices has always been a pain.
One thing that I've found helps is changing the ports different devices connect to, effectively rebalancing power draw and bandwidth usage across the internal USB hubs on the motherboard. I found that the Amplifi recording was working when it was the only thing plugged in to USB, so I don't think it's an issue with the amp.
If you don't care for/need USB 3.0, you can also try disabling XHCI mode in your BIOS.
I got so frustrated debugging this that I bought separate USB 2.0 and 3.0 PCI cards. :o
