ok what i did was make my connections with the 4 cm and then the cable from the ext amp to the back of the amp. then in command center i highlighted a switch that i wanted to use to change channels, i turned the command knob to ext amp and left the select knob at tip. then in global settings in preferences i turned the exp2/ext amp to ext amp out. now you should be able to change channels with the helix. now unfortunately the hum issue is a ground loop that i am waiting to get an ebtech hum eliminator to arrive and then you just put it between the helix send and amp input to lift the ground loop and kill the hum, i will update when it arrives.
hopefully that helps you abit