My humble iPad Air 2 has been updated to iPadOS 14, and my SonicPort (not VX) works just fine.
Tested with Audiobus 3, Overloud TH-U, GE Labs (Mooer), AmpliTube, AmpKit, ToneStack Go, Mobile POD, VStomp Amp HD, BIAS Amp 2. All working.
For some reason, other Positive Grid applications (BIAS FX, BIAS FX 2, JamUp Pro) are very unstable and crash easily. But I guess that it has nothing to do with Sonic Port, they probably need to be updated.
Best