I'm having this same issue. It is very disheartening considering the amount of time I've spent setting up my patches for live performances. (hours and hours of time). I bought this unit new through Musician's Friend. Set it up, and then within a week, one of the control knobs seized up. I sent it back to Line 6 and had it repaired. They sent it back to me with factory resets, so I had to set it up all over again. Fast forward to my first live show and I plug in only to get a really loud hum/buzz. I thought maybe it was the power source or lights, but when I bypassed the effects pedal it was perfectly silent. I'm going direct into the front of my Marshall Vintage Modern. I tried switching to 4 cable method through effects loop and it was the same. I'm not really happy about this and am going to ask for a replacement unit. I'm hoping there is some possible way to store and reload my patches rather than starting from scratch again.
