@reginaldStjohnThanks for the quick reply. So I tried the things you said, now my noise is gone on the XLR jack, but it's still on the 1/4 inch output.
Right now I'm using an instrument cable that I think is suboptimal. Now with the working XLR it's fine for me, but it would be interesting to know if the balanced cable from Helix 1/4 inch to my interface would solve the problem.
Another thing I discovered is that if I connected the Helix to the Mac via usb, but didn't select it as an input or output device in Logic X, the noise wouldn't be there. The moment I select the helix in Preferences>Audio>Devices (no matter if as output or input device) and click "Accept Changes", the noise appears.