Try turning off all sound drivers except the driver needed for your interface. (Line6 ASIO driver.) If you have more than the one driver enabled for your OS or other programs crash can occur. turn off all windows OS sounds. Also check that your ASIO sample rate in settings/sound/driver settings, matches the sample rate in your DAW preferences/settings. Took some research and kind help from other more tech savvy forum users ,but now my pod hd pro won't be a boat anchor this summer! Good Luck. Peace!
