Hey,
sorry.. not enough info.. my bad. I´m a long-time Line 6 user. Started with the original POD way back.
Using the UX1, POD Farm 2.5 for many years on different computers. Recently updated POD Farm to 2.57, maybe it´s a driver issue, rollback was my next step to find the error source.
I thought it´s the MKII, but today the distorted sound also occured when it even wasn´t connected when starting Windows.