See my comments here http://line6.com/support/topic/13832-variax-standard-initial-thoughts/ - the neck is slightly narrower than my strat with similar string spacing so less fretboard at the edges but no string slippage issues for me so far - I mention in my post it has a very flat fretboard.
Comfort wise - it is lighter than my Fender strat - haven't measured scientifically but quite a bit lighter from feel. The neck is not as comfortable as I am used to although hard to say why - possibly because it is narrower I think I am having more of my hand come around the top than normal. Great if you use your thumb on the bass strings a lot but just takes a bit of adjustment I think. Generally though it feels good and plays well - my issues are mainly with the modelled sounds - as a basic electric guitar it is actually better than I expected.
