after upgrade my mac mini, pod farm does not see my usb interface, looking for a solution on another software for amp emulation I end up with ampLion software who after install suggest me to create a aggregate audio device..guess what that's what the solution to have pod farm working on mac os Sierra.....is sad that line 6 don't give any advice neither comment about this issue with mac os Sierra.
https://support.apple.com/en-us/HT202000
https://shop.audified.com/products/amplion-pro-1