Very similar problem here. My Pod HD500X is only a few months old, and yet it showed signs of madness yesterday evening during rehearsals. I was using the fourth patch on a bank, and while playing it suddenly switched to the second patch, and this happened at least five times in a row. As Shadowchild suggested, you usually go through the mental process of thinking "maybe I hit it by mistake" or "maybe it was a power surge", but when I saw it change on its own several times under my eyes, I could definitely tell that it was no mere coincidence. I'm sure the button had been pushed down completely, and I also tried switching off and on (restart) the Pod, to no avail. I even noticed that the temporary pop-up screen (when you modify the settings of a patch on the fly) would stay visible for less than a second before switching back to the "generic" view, as if there were some sort of short circuit or instruction from the Pod itself to "switch back" or "change preset". It had never happened before, and I followed all the recommended procedures, most of all updating the firmware. Now my only chance is to wipe the internal memory clean, reinstall the latest firmware and start again, hoping that it won't fail me this Sunday, when I’m playing a concert with my band. I would be very disappointed if i had to ship my Pod back to repair after only three months (and I probably should already, because something is clearly wrong here!).