Hello same Problem Here i have read through all the post this is totally me also It happens to me on just About Every patch plays fine for a minute or so then you see the Dial on volume go down from 7 to like 3 turn it back up min or so later turns back down to 3 go figure Im using Head phone out so no vibration here ? I will try opening it looking inside clean it up real good clean all the nobs and pots real good check the cable connections real well and get back to ya i have ran line 6 monkey everything is updated to the newest version I will let ya know how it goes soon