It's upon bootup, but it has happened both right after a specific patch and after 1-8 days of working fine. Editing everything/anything I want on the unit doesn't affect the real time operation. It's just once I save, play it for a while, then come back the next day, the switches stop responding. At first I thought it had something to do with HX Edit, so I created my preset manually this time off of a fresh factory reset. It worked fine for 8 days and now it's back to doing the exact same thing. I am using more features than I ever have before in the signal chain (an expression controller, moving parameters with snapshots, renaming snapshots, changing color rings, etc.) but thats because I'm trying to trust the HX effects to be my only effects solution. Those features are EXACTLY what makes me want to use it, but if it really can't handle everything the feature sheet says it can, I'll have to find some other product(s) that will. I freaking love this effect, but the idea of showing up to a gig and having to rebuild everything I've worked on is terrifying.