I am using it with Reaper and Mixcraft, the mics work great but pluging guitar straight in is a little too hot of a signal (humbuckers) and clips alot. without additional windows software there is no way to adjust the input that I can figure out. I guess windows users are going to need more hardware between the guitar and sonicport. I was planning on taking it back but I am thinking about keeping it and just running hardware sims through in on the line in input.
If your driver is installed properly you should be able to go to you Preferences or Options menu and switch to Asio and see the sonicport.