i tried to install my Podstudio UX2 on an iMac without success. I have exact the same issue as described above.
The Monkey detects the device without any issues, but the license manager can not see the device, just the computer.
I tried different versions of drivers, monkeys and license managers without luck.
The MAC OS is 10.7.5 and at the moment all Line6 software including drivers is the newest available.
Side Note: On my Windows PC all works without any issues. License manager can see the device and all is correctly managable.
As a final step, I took a look to the diagnostic log of the License manager on MAC, in one line it says "Device not supported" , maybe this helps.
Many thanks in advance for any help !