I have the exact same problems, 2 jtv 89s. 6th string sounds awful, plainly and almost harmonic overtone in Most models, especially Spank and Lester. I did the same test with switching the piezo connection on 5th and 6th string. Then, 6th string was fine, 5th string then had the awful sound. This means both the mechanics of the 6th string were fine, as was the piezo on the 6th. I'm sorry, Line 6 technician, but your argument that if the electronics were replaced than the issue can't be with the electronics is ridiculous. You could only make that statement if you took the electronics out of a known-working guitar, and put into a second guitar, and the 2nd one still did not work. if you replace defective electronics with more defective electronics, that does not prove anything. That's like saying you changed a flat tire, but put on a different flat tire and then say the bumpy ride can't be the tire, I replaced the tire. Admit there is a problem. Your customers will be much more likely to remain customers, if you can admit it and state you are working on a solution. If not, you will lose customers at an alarming rate.