I have the exact problem. Tried to use Line 6 Updater per support's suggetion and it didn't work. I'll update this reply per my ticket gets updated.
I've been struggling with the same issue for a while now. The driver is not working with my windows 10 home edition. I have installed "Line 6 Driver2 Spider V v1.87 Installer" (the latest so far) yet still, I am getting Code1 error. I tired uninstalling and using previous drivers, result is the same.