I had the same issue. Windows 10 PC. PC has no issues. I downloaded line6 update.
installed updater on my PC, rebooted my PC. logged into desktop
Powered on Helix, connected usb, my computer DINGED and detected the USB.
When I launched my updater, it would not detect the helix floor.
I Powered off my helix, powered off my PC.
Powered on/logged into the PC. Powered on helix, connected usb, ran updater .. still did not detect helix.
CLOSED updater.
I removed all my cables to my helix, leaving only power. powered off helix.
I powered it on with just power cable. Connected USB and it detected it on my PC.
I know that seems odd but that is what worked for me.
