I realize this board is not well traveled, but there are at least a couple of you that I see respond to many of the posts and have extensive experience with both products I'm evaluating.
Quick Background: I have been playing with a Helix at church for about 3 years, and we use a silent stage. At home I generally practice with my HS8's (running tracks, and sometimes Helix Native via my Scarlett Solo interface). Sometimes I will plug my guitar into an amp and play along with the tracks coming out of my HS8's. A few months ago I purchased a PC112+ after wanting one for years - it was great, but I started to 2nd guess the nearly $700 I spent on it when I could get a Catalyst 100 for just over half the cost, and it was a stand alone amp to boot. I ended up buying a Catalyst 100 and tested it side by side with the PC112+. Ultimately I prefered the PC112+ but couldn't justify how expensive it was relative to the Catalyst, so I returned the PC and kept the Catalyst. Fastforward to now and I recently picked up a used PC112+ for $400. I'm pretty sure I am going to take a loss on the Catalyst and sell it to keep the PC112+.
As I'm testing them out, I've read that many people feel the Catalyst works as a great companion to the Helix, and people leave the Helix patch alone and plug into the poweramp in on the Catalyst. When I do this, I'm dissapointed with how it sounds. I've tried disabling IR's or cabs in the helix, and on some things this can sound "ok" and other amps it sounds like trash. Am I doing something wrong or is this really just an "ok" solution that those with a Catalyst are doing when it actually doesn't sound good at all and a purpose built FRFR (or Powercab) works much better with the Helix? I feel like I MUST be missing something how many times I've read folks praising the Catalyst paired with a Helix.