I knew I would loose all of my presets, I was just so frustrated I did it anyways. I worked as a Post Data Sales Engineer for 23 years.
There has to be something that is missing that either the amp is looking for or the HX. Like maybe a current of some sort, or specific resistance (4ohm, 8 ohm, 16 ohm etc..).
I tried Line/Line, Line/inst, inst/inst, & inst/line nothing worked. The oddest part is if I put the HX in Analog Bypass I could get normal sound, but if I engaged the DSP's it would not pass the sound. So far every other amp I've tried it in has worked. I'll keep digging and see what I can find. If I find a solution I'll post it. Surely, I am not the only one that has had this issue..