Thanks for the advice, everyone.
My experience with tube amps has been limited. My thinking is to get the dt50 1X12 with the option of the extra cab if I ever needed it. Now I might need to consider the 25w version!
For the distortion effects, I agree that an independant pedal is usually better(the only pedal I use is an Ibanez tube screamer from Analogue Man). I was mostly curious if the effects, overall, are more refined than previous efforts by Line 6. I play in a rather ecclectic band that requiers me to go from clean-surf-metal-jazz-rock tones within a given set. But hey, that's why this technology is so awesome!
Concerning the hum in the Vetta, it is definitely more noticeable in certain outlets than others, but always there to a degree (I am aware of how grounding can effect this).