Ok, Im joining this thread, as I have identical problems, with BSOD spitting out all kinds of different messages, KERNEL etc etc. I thought it was just my Razer laptop that had bad hardware, but on seeing these posts I see it may by Line6 drivers at fault.
Also, i cannot use line6 HD500 with USB while computer power is plugged in to power. I know this is an ongoing earthing problem that Line6 seems to not have a simple solution too.
Quite disappointing if solution is to buy a Helix. I would prefer not to, as it only encourages line6 to not fix older hardware issues.