Well I'm a newbie, 3 wks in...old school for sure, I like consistency, so I tried the global eq approach, tried getting the signal hot approach also, down loaded the relevant 4/5 star custom tones for my tastes, levelled all of them to a consistent hot'sh reasonable level via master output, thinking signal is everything.., 3 worked out of 70 thorough a PA set up..I did have luck my 1st time w/ a PA with a 2204 preset keeping the levels matched to the by passed signal when I was auditioning & considering the Helix, and it convinced me it had the goods, along with the major studying of the Helix via all the forums.... ..so I'm now trying to find a method for finding a solid core tone, and find a way out of this rabbit hole, I've started a project of a preset for every amp (49)..I have them all set with no global eq, all have stock mic at 4", Low cut 50-80hz-Hi Cut 4-9hz, I'm starting now to tweak the gain stages and eq's...keeping the channel vol at least to 5, dropping the presence down to almost nil and keeping the levels as close to bypass as I can with no adjustment on the output stage, I realize this is probably backwards all these amps are different and will react and benefit from differing approaches ...I mean when I went through those 70 fairly rockin presets, I figured one of the Marshall amps would pop out as solid, they sounded great tweaked through my Roland CM-30, but it was a Matchless that kicked butt and was solid, I'm hoping there's a rational reason why and I'm hoping it's not a different reason for every amp other then eq or gain staging, the previewing of the options and cycling through is daunting, I'm gonna have to try the looper trick..thanks ...still I really dig what Line 6 has done here with Helix, so I'm in even if it never hits a stage, anyway just hoping to achieve a knowledge base, I guess I'm a little new to be in this thread, I have to say this thread has been enlightening thanks to the OP...