Sorry if it's not exactly the same as I was tweaking and trying things, puting the fx loop pre and post amp, but amp and fx loop blocks are the same, I'm not trying to mislead or anything.
Pedals I've tried: Plethora X5, Boss Rv-3, Source Audio EQ, Ibanez TS-9, Boss RC-1 and everyone of them causes the issue, the only one that worked fine was the TC Spark mini (maybe because it's a tiny circuit), that made me think it's an send/return impedance issue, since there's no option to tweak it, and it really souns like I'm runing a 30 pedal chain, tomorrow I'll try using a buffer.
That said, does the fx loop impedance changes depending on it's placement on the chain?