The POD becomes your soundcard essentially so your mobo sound is inactive,so as above if you wanted to hear everything you will need to use the outputs of the POD.
As for speakers the sky is the limit really. Last night i couldn't be bothered firing up the pc so plugged in a pair of logitec pc speakers to the 1/4 output.
Get a few 1/4 to 3.5mm adapters and you will have a tonne of options.