Thank you for the tip. I am using Klipsch R51-PM monitors with Studio One and Presonus 26c connected to my computer. I am so new to this, so that any advice would be excellent. I use my setup to learn guitar, record song ideas, and record myself playing along to songs. I took a 35-year hiatus from playing and trying to recreate the sounds of my favorite guitarists. I usually play the guitar amped by the Spider and use Studio One to play songs through my R51's. I could connect the Helix to the R51's by USB, but don't you think shoving my guitar and the song playback through the R51's would be too much? As I said before, I am pretty much a newbie at this, and if you could elaborate on the "tweaked my presets to my studio monitors," I would so appreciate it. I expect my Helix to ship in March, so I am reading up on the manual to gain some insight before I jump in. Thanks again for your help!