I am having the same issue and can't make any sense of all these forums. I have a Mesa Mark 5 35 combo. When I do the 4 CM I lose all Volume control. None of the nobs on the amp do anything. This seems stupid. I want to use the system as if it where all small pedals.
1. Distortion , compression and any other cool effect running up into the Mesa Pre Amp.
2. Then I want to send all Chours and Delay and Tremolo effects to the FX loop.
This how I ran pedals prior to getting this board and can't figure out why the darn thing is so complicated to get to work that. Do you have to add send/return blocks? Is this What path A is verse Path B. You would think this came with instructions.
Forgive my typos.