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This thread may help setting up.

I use FBV express MK11 in reaper. check link

I use FBV Express Mk 11 in native. Check this link.

As promised... How I set up controlling snapshot changes etc in Helix native using Reaper and a midi foot switch. This relates specifically to Line 6 FBV Express MK11 but would be applicable to other Midi devices. helix native midi control in reaper.pdf

I have been using an FBV express mk11 for a couple of months now to control native using reaper. I use it to change snapshots and start and stop recording. I can use the expression pedal for Wah etc. It took a long time to work out and I will need to make myself familiar again with the steps. Give me a couple of days and I will post what I had to do.