I seem to be having this problem too, and I have 2.82 fw installed.
I was working on an 8-snapshot patch that contained the LA Studio Comp and the Red Squeeze too. All of a sudden, while editing, almost all the settings of almost every block turned to some previous state (Default values mostly). I had a clean snapshot, crunch, distorsion, lead and more, and I ended up with 8 almost identical snapshots. The outputs were set up all different, and they all ended up at +0.9 dB, that sounds like a very random value, or maybe it was the value one of the snapshots had, not sure about it.
I started all over again and after some time it happened again, 4 times in total. I was editing with HX Edit on my Mac.
I can't say for sure what was that triggered the reset. I did everything back again directly on the Helix LT, and I think that the issue did not show up, but I am still not completely sure, sometimes I had the impression that I had to move some knobs more than once. I haven't booted the Helix again after all was set, so I can't say if the problem persists.
All of my presets have the LA comp at the end of the chain, like others commented, so all of my patches might have had the same problem and I still haven't realized it. I'll have to check. What's for sure is that the LA comp was on the patch I was working on today.
I am a new Helix user, and this is my first modeler (I have always been a tube amps+stompboxes kind of guy). I have to confess that the temptation to sell it and go back to analog is strong at the moment. So much work is involved in building patches, and of course you rely heavily on them. If such a problem happens right before a gig, what can you do?